Bristol-Myers Squibb: In the Pipeline
 
 
 

In the Pipeline | December 31, 2014

Compound /
Generic Name

Brand Name

Phase

Modality /
Compound Type

Disease
Areas

Factor XIa Inhibitor
1
Small Molecule
Cardiovascular
Apixaban
M
Small Molecule
Cardiovascular
IKur Inhibitor
2
Small Molecule
Cardiovascular
PAR4 Antagonists
1
Small Molecule
Cardiovascular
CCR2 / 5 Antagonist (1)
2
Small Molecule
Fibrotic Diseases
Galectin-3 Inhibitor
1
Small Molecule
Fibrotic Diseases
CCR2 / 5 Antagonist (2)
1
Small Molecule
Fibrotic Diseases
LPA1 Antagonist
2
Small Molecule
Fibrotic Diseases
Anti-Myostatin
1
Biologic
Genetically Defined         Diseases
Anti-eTau
1
Biologic
Genetically Defined         Diseases
Anti-KIR Lirilumab
1
Biologic
Immuno-Oncology
Anti-LAG3
1
Biologic
Immuno-Oncology
PROSTVAC+
3
Biologic
Immuno-Oncology
Nivolumab
M
Biologic
Immuno-Oncology
Anti-CD137 Urelumab
1
Biologic
Immuno-Oncology
Ipilimumab
M
Biologic
Immuno-Oncology
Elotuzumab
3
Biologic
Immuno-Oncology
Anti-CD40
1
Biologic
Immunoscience
Abatacept
M
Biologic
Immunoscience
S1P1 Agonist
1
Small Molecule
Immunoscience
IRAK4 Inhibitor
1
Small Molecule
Immunoscience
Anti-CD28 Lulizumab
2
Biologic
Immunoscience
Belatacept
M
Biologic
Immunoscience
Anti-CD40L
1
Biologic
Immunoscience
BTK Inhibitor
1
Small Molecule
Immunoscience
MGAT2 Inhibitor
1
Small Molecule
Metabolics
PEG-FGF21
2
Biologic
Metabolics
Anti-Fucosyl GM1
1
Biologic
Oncology
Anti-CXCR4 Ulocuplumab
1
Biologic
Oncology
Notch Inhibitors
1
Small Molecule
Oncology
Anti-HER2
1
Biologic
Oncology
Dasatinib
M
Small Molecule
Oncology
Anti-PD-L1
1
Biologic
Virology
Daclatasvir
DAKLINZA^
M
Small Molecule
Virology
Atazanavir sulfate
M
Small Molecule
Virology
HIV Maturation Inhibitor
2
Small Molecule
Virology
HIV Attachment Inhibitor
2
Small Molecule
Virology
NS5B Non Nuc Beclabuvir
3
Small Molecule
Virology
Asunaprevir
SUNVEPRA*
M
Small Molecule
Virology
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Explore Our Pipeline


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Development Phase
1 - Phase I
2 - Phase II
3 - Phase III
M - Marketed Product       Development
Modality/Compound Type
Biologic
Small Molecule
Disease Areas

+PROSTVAC added March 4, 2015
^DAKLINZA is not approved in the U.S.
*SUNVEPRA is not approved in the U.S.

Please click on product name to see the Full U.S. Prescribing Information for ELIQUIS®, ERBITUX®, NULOJIX®, ORENCIA®, REYATAZ®, SPRYCEL®, YERVOY®, including boxed WARNINGS for ELIQUIS®, NULOJIX®, and Boxed WARNING for YERVOY® regarding immune-mediated adverse reactions and Boxed WARNINGS for ERBITUX® regarding infusion reactions and cardiopulmonary arrest.

Phase I – clinical trials investigating safety of an investigational medicine in a small number of human subjects.

Phase II – clinical trials investigating dosing, safety and efficacy of an investigational medicine in a small number of patients who have the disease or condition under study.

Phase III – clinical trials investigating the safety and efficacy of an investigational medicine in a larger number of patients who have the disease or condition under study. For purposes of this chart, this includes the regulatory approval process prior to receiving marketing approval in the first major market.

Marketed Product Development – clinical trials investigating new uses or formulations regarding medicines that have already received regulatory approval for at least one indication in a major market.

Like any other scientific endeavor, clinical testing of novel drug compounds is a complex, time-consuming, resource-intensive process with no guaranteed results. But, as described here, Bristol-Myers Squibb is committed to pursuing such clinical development and, in doing so, to bringing new hope to patients.

 
 
 
 
 


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