Cardiovascular Institutional Senior Territory Business Manager, Eliquis in Southern Maryland

Achieves sales objectives in assigned institutions/hospitals by developing and executing an effective sales plan and generating prescription demand for assigned products.

Duties and Responsibilities

Develops and executes local business plan to increase market share by outlining strategic drivers, tactics, and applying resources to appropriately promote assigned product(s) to health care providers, hospital administrators, key influencers and ancillary hospital staff along the patient continuum within a geographically defined area.

Develops and executes innovative strategies to reach difficult to access health care providers and accounts in a compliant manner.

Develops and leverages strong professional relationships with customers in clinical practice, pharmacy department, pharmacy and therapeutics committee (P&T) and other key influencers to encourage formulary access and product availability throughout the Integrated Delivery Network (IDN), health-system or individual hospital.

Works collectively with matrix and alliance team members to arrange approved promotional programs, displays and hospital initiatives that will effectively and compliantly promote assigned products.

Establishes and maintains excellent communications and sound working relationships with matrix and alliance team to facilitate the sale of assigned products and enhance customer relations at the territory level.

Demonstrates thorough understanding of disease state, BMS products and relevant competitor products, including: product characteristics, mechanism of action, indications, efficacy, safety, access/affordability & reimbursement services and payer/formulary

Ensures adherence to and compliance with all relevant laws, regulations, company policies and procedures.

Other related duties as assigned to meet departmental and Company objectives.

Qualifications

Experience as full time Institutional Cardiovascular sales representative or prior account management experience working with health systems, hospitals and medical groups is strongly preferred.

5 years of healthcare sales experience or transferable skills are required.

Demonstrated ability to achieve and exceed sales objectives.

Experience at identifying, engaging and establishing rapport and credibility with key decision makers such as health care professionals, hospital administrators and others involved in the patient continuum of care.

Demonstrated ability to analyze data and understand industry trends to build business plans and grow the business in assigned territory.

Strong clinical selling and business acumen skills

Experience cultivating collaborative relationships with matrix and alliance teams in order to accomplish shared objectives.

Demonstrates ethics and integrity at all times

Bachelor's Degree is required.

Must reside within a 50 mile radius of the territory epicenter or within 50 miles of an assigned hospital in the geography.

Management retains the right to change the job specifications (may include grade level and salary range) and provisions of this job as appropriate. In addition, we reserve the right to place candidates in positions at levels commensurate with their depth of knowledge around the following competencies: Product and Disease State Knowledge, Market and Industry Knowledge, Sales Resource Utilization, Selling Skills, and Business Planning.

As this position requires operation of a Company-provided vehicle, offers of employment are contingent upon the candidate meeting the requirements of “Qualified Driver,” as determined by the Company in its sole discretion, including but not limited to the following: 1) at least 21 years of age; 2) a driver’s license in good standing issued by your state of residence; and 3) a driving risk level deemed acceptable by the Company.

Bristol-Myers Squibb (BMS) is a global Biopharma company committed to a single mission: to discover, develop, and deliver innovative medicines focused on helping millions of patients around the world in disease areas such as oncology, cardiovascular, immunoscience and fibrosis. Bristol-Myers Squibb has built a new state-of-the-art Multi-Product Cell Culture biologics manufacturing facility in Ireland, Cruiserath, Dublin 15, approximately a $1 billion investment. The new facility will significantly increase Bristol-Myers Squibb’s biologics manufacturing capacity and play a central role in its global manufacturing network.

BMS Cruiserath Biologics is seeking to recruit a QC Biologics Separations Analyst on a permanent and fixed-term contract to join the QC-Separations Laboratory, the function of which is to support drug product and drug substance release testing. The successful candidate will be involved in assisting in the establishment of laboratory operations, performing testing of samples and performing laboratory duties in accordance with cGMP regulations.

Key responsibilities will include, but not limited to:

• Performing release testing for biological products
• Assisting in updating and issuing documentation, including SOPs, as required.
• Performing routine data analysis, assist in the investigation of OOS results, perform trending analysis and writing investigation reports.
• Accurately documenting laboratory work.
• Execute and assist in technical transfer and co-validation activities.
• Assisting with qualification of laboratory instruments.
• Data review based on demonstrated proficiency on assays.

Qualifications and Experience required:

• 1-2 years’ experience in a regulated biopharmaceutical laboratory is essential. Some experience in Capillary Electrophoresis or Empower would be an advantage.
• The ideal candidate should hold a minimum of a BSc. in Biochemistry or related discipline.  
• The successful candidate must demonstrate an ability to work independently in assay and recognize anomalous trends or results.
• The successful candidate must demonstrate problem solving ability, as well as the ability to prioritize objectives from multiple projects and adhere to scheduled timelines.
• Excellent communication and the ability to work in a team based collaborative environment are required.
• Employees are expected to display the BMS Biopharma Behaviours, which enable them to be successful and perform at their highest level. The BMS Behaviours are: Passion, Innovation, Accountability and Speed.

Why should you apply:

• You will help patients in their fight against serious diseases and you will increase the survival of more people with cancer
• You will be part of a company that encourages excellence and innovation, respects diversity, develops leaders and values its employees.
• You’ll get a competitive salary and a great benefits package including an annual bonus, pension contribution, family medical allowance, 23.5 days annual leave plus 3 Company days,  life assurance and gain-sharing bonus.

Join us and make a difference

At Bristol-Myers Squibb, we’re creating innovative medicines for patients who are fighting serious diseases. We’re also nurturing our own team with inspiring work and challenging career options. No matter our role, each of us makes a contribution. And that makes all the difference.  We hire the best people and provide them with a work environment that places a premium on diversity, integrity, collaboration and personal development. Through a culture of inclusion, we create a better, more productive work environment. We believe that the diverse experiences and perspectives of all our employees help to drive innovation and transformative business results.

- Organise et supervise l’ensemble des activités de Qualification de Performance (QP) et des Validation des Procédés de production sur les sites UPSA

• Participe à l’élaboration des Plans Directeurs de Validation.
• S’assure de la planification, de  l’organisation  et de l’implémentation des diverses activités de QP, validation et re-validation des procédés.
• Garantit le suivi du planning et la gestion des écarts ; assure un reporting régulier de son activité auprès du Responsable Qualification / Validation.

- Apporte une expertise technique dans l’élaboration de la stratégie opérationnelle et la mise en œuvre des activités de Qualification de Performance et Validation des Procédés de production

• Evalue les impacts techniques en termes de validation des procédés.
• Etablit les stratégies opérationnelles de QP et validation des procédés.
• Assure le traitement des documents de validation (protocoles, rapports, déviations, etc.), et statue sur la conformité des résultats suite à exécution.
• Participe à la préparation et déroulement des audits du site  en tant que SME.

- Encadre l’équipe de Validation Procédés

• Encadre et anime une équipe de collaborateurs.
• Optimise les moyens humains et matériels dont il (elle) est en charge dans le but d’une amélioration continue

1. External Environment and Customer Focus

• Develop and maintain strong relationships with Thought Leaders, appropriate HCPs, and access stakeholders, within a given geography to answer scientific, unsolicited product and HEOR related questions. SAs will use various channels for interactions (1:1, group presentation; remote, etc).
• Effectively present information to HCPs, as appropriate, ensuring medical accuracy and compliance with local procedures, ethical and legal guidelines and directives.
• Actively profile the medical landscape and continuously update knowledge and expertise in products, patient treatment trends, unmet medical needs, clinical trials and scientific activities. Understand the competitive landscape and actively prepare to address informational needs of customers.
• Collect and provide meaningful medical insights back to the medical and commercial organizations to be actioned in support of the strategy development.

2. Manage and Deliver the Medical Plan

• Provide strategic input into the development of Brand plans, develop and execute local Medical Plan and TL Interaction plans.
• Deliver scientifically meaningful medical program proposals and ensure flawless execution of medical activities
• Identify potential speakers for BMS educational programs and ensure that these speakers receive all necessary product and disease state training.

3. Provide Medical Support

• Contribute to the development and review of medical content within promotional and non-promotional materials (as appropriate, consistent with the Promotional and Non-Promotional BMS procedural documents and/or local codes), according to local resource and requirement.
• Contribute to and coordinate the development of the medical / scientific sections of pricing and reimbursement files.
• Contribute to the development of scientific publications or presentations, as appropriate. 
• As necessary and appropriate, may support the initial and ongoing medical/scientific area and product specific training and provide key scientific updates to internal stakeholders (Commercial, Regulatory, OR, PV, Legal, HEOR, Market Access, etc).

4. Support Clinical Trial Activities

• Support Interventional and Non Interventional Research (NIR) studies (including input on study feasibility, identification and assessment of potential study sites, facilitate BMS and investigator activities, and conduct site visits to support patient recruitment and/or discussions around the safe and effective use of BMS investigational products, as appropriate and in agreement with local medical management.
• Provide recommendations and insights to GDO on study and site feasibilities within the therapeutic area based on knowledge of the field and through direct contacts with potential investigators, as appropriate and in agreement with local medical management.

• Actively support CRO sponsored studies as appropriate or as defined by the study scope document

• Provide medical support to GDO to transition patients from clinical trial to marketed and/or reimbursed supply of drug, where required and appropriate.

• Ensure that BMS Pharmacovigilance procedural documents are understood and applied by Investigators of local studies, and alert appropriate BMS personnel to any identified Adverse Events.

Summary

Responsible for leading a group of medicinal chemists in the identification, synthesis, and characterization of novel drug candidates for the treatment of cardiovascular diseases.  Takes accountability for the delivery of the complete synthetics portfolio in Cardiovascular Diseases, exploratory phase to GT2, in partnership with counterparts across Discovery.  Within Discovery Chemistry, mentors teams to collaborate effectively with the Pan-Therapeutic Area Chemistry, BBRC Medicinal Chemistry, Discovery Chemistry Platforms, and New Modalities in order to ensure program objectives are met.  The individual will report to the Head of Innovative Medicines Discovery Chemistry.   

Responsibilities

Takes on activities associated with Group Director-level management.  Establishes strong partnerships and effectively interacts with Discovery Biology and PCO counterparts as well as with external partners for collaboration programs, determines program objectives and sets criteria for program evaluation. Develops alternate plans when needed and sets priorities.  Makes recommendations for appropriate allocation of resources. Understands organizational needs and develops scientific and technical solutions across functions, departments, and the global business.  Anticipates needs, assesses and manages risks and organizational dynamics as well as their implications.  Contributes to the development of publication strategies for cardiovascular programs/assets, and coordinates preparation of medicinal chemistry publications according to publication plans. Develops strategies to monitor competitor activities such as patents, publications, and external meetings to optimize the proprietary position of programs in area and understand positioning of these programs relative to competitors. Communicates effectively in oral and written presentations to a variety of audiences, both internally (e.g. governance forums, team meetings) and externally (e.g. manuscripts, scientific meetings, business development activities).  Creates, innovates, and champions new approaches, and demonstrates flexibility, open mindedness, and adaptability to a rapidly changing environment. Provides scientific and managerial direction, leadership, and assistance to others in an effective manner.  Establishes team roles and responsibilities, provides direction, fosters effective team skills, and assures high quality results are produced in a timely fashion. Consistently develops people, is attentive to succession planning needs, and effectively resolves difficult situations.

This is a key leadership position within the Cardiovascular & Fibrosis Discovery Biology organization reporting directly to the Vice President and includes participation on the senior leadership team. 

Responsibilities

Line Management of multiple PhD scientists and their associate scientists

Setting drug discovery strategy for cardiovascular R&D

Leading new target acquisition efforts

Assisting with technical due diligence activities for in-licensing opportunities

Co--leading drug discovery working groups 

Representing CV Discovery on clinical development teams.

Qualifications

Position requires a PhD in Biochemistry, Cell Biology, Molecular Biology, Pharmacology or related field, with a demonstrated expertise in the cardiovascular sciences based on publication record and/or a clear track record of successful delivery of cardiovascular-related drug discovery projects.  

An MD degree with extensive post-doctoral experience in the above fields will also be acceptable.  

Experience in the sub-field of heart failure would be a plus.  

The position also requires 15+ years experience in biopharmaceutical drug discovery in an industrial setting and demonstration of excellent communication and people management skills.

The key responsibilities for the role include:

• Support Drug Supply Managers and their assigned programs through the creation and management of clinical trial demand forecasts and budgets with consistent and clear process outputs.  Administer the forecasting process at multiple times and at multiple levels of granularity in alignment with downstream supply chain requirements.  Through robust and formalized communication of key clinical demand drivers, organize and manage key forecast parameters which impact demand volumes and timings.  Assess pertinent factors in determining and developing forecasts at either the program or protocol level.

• Develop an understanding of clinical trial operational expectations by reviewing the study design, expected pace of enrollment, dosing schedule, study assumptions and resulting demand forecasts.  Aid the CSS organization in the creation and management of IRT algorithms based on predicted conduct of clinical trials and established forecasts.

• For assigned programs, monitor the R&D clinical book of work to ensure adequate representation of clinical demand forecasts.  Collaborate with Drug Supply Managers in understanding trial timing, asset strategy and study design/protocol availability.  Identify clinical trials requiring forecasting, to aid the R&D Supply Chain in recognizing demands for long lead time operations.

• Lead business process development efforts in support of a nascent Demand Management function, to increase the value of the forecasting function to both upstream and downstream stakeholders.  Lead the development of optimized information technology forecasting tools which will enable R&D Supply Chain excellence, part of the PD strategy.

• Per a predefined business process, update previously established forecasts at a regular cadence and corresponding to the status of the program/protocols being forecasted (startup, maintenance, close-out).  Based on current information related to ongoing studies (real time activity, inventory levels, enrollment, etc.) collaborate with CSS in reforecasting clinical demands.  Aid in leveraging updated forecasts to inform current demand/supply plans and downstream operations.

• Participate jointly with Drug Supply Managers in preparation and presentation of program level forecasts and demand plans.  Attend program level governance meetings  covering demand forecasts for both internally procured supplies and projected comparator drug supply purchases.

Required Skills/Experience:

Communicative: Operate with a high degree of connectedness, transparency and clarity to ensure common understanding of requirements, issues and actions; listen to stakeholders and distill information into pertinent and actionable content.

Analytical: Ability to characterize clinical trial requirements and synthesize data into forecasts of clinical trial expectations.  Ability to merge both firm and changing information sets into reasonable and defendable forecasts.  Prior exposure to statistical modeling and prediction algorithms is a plus.

Responsive: Demonstrate a nimble nature to adapt to the pace and dynamic nature of an R&D environment; process data, information and feedback with speed and communicate outcomes, alternatives and impacts with appropriate urgency.

Expert: Prior experience within a clinical supply chain function; demonstrated experience in clinical forecasting and management of related IT tools such as Smart Supplies, SAP, IRT Systems; demonstrated understanding of clinical protocols and the creation and management of demand plans to support clinical protocols; 7-10 years clinical trials planning experience.

Innovative: Ability to develop new ways of working; understanding of the function of Forecasting in the R&D Supply Chain in order to improve the value proposition to stakeholders; creativity to aid in establishing robust business processes related to the Forecasting function.

Collaborates with category leaders and business partners on category strategy development and leads/supports procurement execution. Builds understanding of BMS’s global, end-to-end value chain as it relates to the categories in focus. With this knowledge, provides strategic industry insights and identifies potential opportunities to improve total cost of ownership, including revenue enhancement, speed-to-market, mitigated risk/improved lifecycle management, and other opportunities that offer BMS competitive advantage. Strives to make positive impact on the organization, short and long term. Manages Supplier Relationship Management processes, procedures, supplier and category segmentation, metrics/KPI development and application, scorecard format, contract management, etc. Through Supplier Relationship Management programs, he/she will facilitate continuous improvement and supplier-enabled innovation and enable the Head of Sourcing/Sourcing Managers to achieve strategic objectives.

Major Responsibilities and Accountabilities:

- Provide internal and market analytics to support development of strategic category plans; collaborate with category leaders and business partners on plan development

- Support and/or lead execution of procurement plans; role dependent on category and project complexity.

- Assist/lead identification and screening/selection of potential sources. Assist/lead in determining appropriate methods of procurement

- Lead the preparation and solicitation of competitive bids, quotations and proposals with pertinent specifications, terms and conditions.

- Employ leading practices

- Evaluate competitive offerings and recommend overall best offer for a product or service

- As part of implementation, review product availability and/or pricing information with suppliers

- Assist in the preparation of and/or issue contracts and purchase orders for legal review and approval

- Support design/development of procurement compliance programs

- Support decision-making and process design to align practices with organizational objectives and sourcing strategies

- Support SRM process through required development and delivery of prioritized performance metrics

- Support risk management efforts as required in category

- Mentor/develop junior staff in Sourcing Excellence (new associates, analysts, co-ops)

- Provide BMS support/oversight to suppliers of Procurement BPO services

Position Requirement: *

• Bachelor's Degree or work equivalent required

• Minimum of 4-6 years of work experience

• Minimum of 2-4 years Procurement experience with 1-2 years in Indirect Spend categories, preferably in Corporate Goods & Services

• Strong written and verbal communication skills

• Proficiency in Microsoft Word, Power Point and Excel

• Proved ability to manage multiple projects/tasks effectively

Bristol-Myers Squibb (BMS) is a global Biopharma company committed to a single mission: to discover, develop, and deliver innovative medicines focused on helping millions of patients around the world in disease areas such as oncology, cardiovascular, immunoscience and fibrosis. Bristol-Myers Squibb has built a new state-of-the-art Multi-Product Cell Culture biologics manufacturing facility in Ireland, Cruiserath, Dublin 15, approximately a $1 billion investment. The new facility will significantly increase Bristol-Myers Squibb’s biologics manufacturing capacity and play a central role in its global manufacturing network.

BMS Cruiserath Biologics is seeking to recruit permanent Maintenance Technicians with 2-4 years’ experience who will execute predictive, preventative and other maintenance activities to ensure the site operations are safe and reliable. The role will provide an opportunity to cross train in mechanical, electrical and instrumentation fields.

Key responsibilities will include:

• Work Safely – identify risks and put in place mitigation actions if required.
• Ensuring that equipment failures or issues are responded to promptly and appropriately in a cross functional environment. Record interventions including failure codes.  Providing guidance and solutions for preventative action where required.
• Executing planned maintenance routines including predictive, preventative and calibration activities.
• Ensuring all Work Orders are completed in a compliant manner and asset management data is captured accurately.
• Provide clear and concise written and verbal handovers to colleagues.
• Participating in project activities and reviews. Identifying job plan activities and spare parts for planned activities.
• Supporting major equipment overhauls and manage vendors when on site.
• Supporting development of training information, cross train colleagues.
• Assisting colleagues and other functions with tasks – i.e. set-up, sampling, cleaning validation activities.
• Working in cross functional teams where Operational Excellence techniques are used to optimise processes.
• Ensuring the site is audit ready at all times, house-keeping standards are always adhered to, training completed on time.

Qualifications and Experience required:

• The successful candidate must possess at minimum a Level 7 Electrical or Instrumentation or Mechanical related qualification.
• 2-4 years’ experience in a maintenance or relevant engineering role in a regulated manufacturing environment is essential.
• Experience in a biopharmaceutical, pharmaceutical, medical device or FMCG facility is required.
• It is essential that BMS Maintenance Technicians prioritise safety, quality and reliability in every task.
• High level of attention to detail in following procedures and must be flexible and open to change.
• Ability to work independently and also as part of a team.  
• Strong problem solving ability and adhere to scheduled timelines.
• Employees are expected to display the BMS Biopharma Behaviours, which enable them to be successful and perform at their highest level. The BMS Behaviours are: Passion, Innovation, Accountability and Speed.

Please Note: Due to the nature of manufacturing operations, shift work will be required as the site moves into 24/7 mode of operations.

Why should you apply:

• You will help patients in their fight against serious diseases and you will increase the survival of more people with cancer
• You will be part of a company that encourages excellence and innovation, respects diversity, develops leaders and values its employees.
• You’ll get a competitive salary and a great benefits package including an annual bonus, pension contribution, family medical allowance, 23.5 days annual leave plus 3 Company days,  life assurance and gain-sharing bonus.

Join us and make a difference

At Bristol-Myers Squibb, we’re creating innovative medicines for patients who are fighting serious diseases. We’re also nurturing our own team with inspiring work and challenging career options. No matter our role, each of us makes a contribution. And that makes all the difference.

 We hire the best people and provide them with a work environment that places a premium on diversity, integrity, collaboration and personal development. Through a culture of inclusion, we create a better, more productive work environment. We believe that the diverse experiences and perspectives of all our employees help to drive innovation and transformative business results.

Senior Research Investigator (IO Resistance Biology)

Bristol-Myers Squibb R&D is a science-driven, passionate organization determined to discover, develop and deliver medicines that have the potential to transform the lives of patients and establish new standards of care in areas of high unmet need. Patients’ needs and scientific discovery are our driving force.   The new Bristol-Myers Squibb research site in Cambridge’s Kendall Square will position our scientific team in the heart of a vibrant ecosystem of world-class science, innovation and business opportunities.  Our scientists will focus on novel targets and pathways for tumors that are refractory to current Immuno-Oncology therapies. These are significant challenges that will require innovative solutions from the biopharma, biotech and academic communities.

Roles and Responsibilities

We are seeking a Research Scientist, who will be responsible for evaluating mechanisms of resistance to IO therapy in the patient setting. Experienced candidates will have have working knowledge of the refractory IO landscape and have been exposed to the theories and implications of the newly evolving field of acquired resistance. The Research Scientist will identify and evaluate molecular and cellular signatures that can be explored to tease out the mechanistic underpinnings as to why some patients fail IO therapy. A broad working knowledge of genomics, proteomics, preclinical modeling and cellular biology with exposure to various technology enabling platforms, addressing questions in the clinical context is required. The candidate will be expected to partner closely with our bioinformatics, pathology and “omics” teams onsite and will participate in internal and external scientific meetings, presenting their data and critically evaluating emerging scientific literature and technologies to contribute to the projects they are assigned to. We are seeking a self-motivated, proactive contributor for a dynamic, fast-paced multidisciplinary team.

Qualifications / Essential Skills

MD/PhD or PhD in cancer biology, or equivalent advanced relevant biology degree

Experienced scientist with 3-5 years’ of post-graduate research experience, with a minimum of 2 years post-doctoral studies in a clinical or translational setting

Candidate will have in-depth knowledge / understanding of the cancer therapeutic landscape utilizing NGS platforms to tease out mechanistic insights with respect to response and resistance to a given therapeutic regimen

Participated in clinical studies to better characterize the molecular underpinnings of therapeutic resistance in patient cohorts and correlation with clinical outcome

 A track record of independent critical thinking and scientific achievement demonstrated by first authorship in recent high impact publications

Exposure to cancer immunotherapy including immune-checkpoint blockade with knowledge of current therapeutic landscape is highly desirable

Recent experience in supervising bench scientists in an academic or industry setting is desirable

Experience in balanced experimental design, data visualization and working knowledge of NGS pipelines and statistical analysis tools are desirable

Excellent interpersonal skills and ability to communicate, both written and oral effectively and efficiently within the BMS organization and with external partners/collaborators

Thrives in fast-paced, dynamic work environment, bringing a pro-active mentality to the role

We follow the science and we’ll continue to invest in translational medicine research, deepen our understanding of disease biology and uncover insights about predictive biomarkers with the ultimate goal of making precision medicine a reality for more patients.