At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

Attached

Aufgabengebiet:

Als Clinical Site Monitor (m/w/d) betreuen Sie, homebased, Studienzentren in Deutschland, Österreich und der Schweiz. Sie initiieren, überwachen und evaluieren klinische Studien verschiedener medizinischer Fachbereiche und Indikationen. Durch regelmäßige Besuche an den Prüfzentren stellen Sie die korrekte Durchführung der Studien sicher. Mit dem Zentrumspersonal halten Sie stets engen Kontakt ob direkt vor Ort, telefonisch oder per E-Mail. Auch eine intensive Zusammenarbeit mit unserem gesamten Studienteam in der Hauptverwaltung ist für Sie selbstverständlich.

Anforderungsprofil:

Sie haben ein abgeschlossenes naturwissenschaftliches Studium oder eine medizinische Ausbildung (z. B. als Arzthelfer/in, MTA) und bringen neben sehr guten Englisch- und PC-Kenntnissen idealerweise Berufserfahrung im Monitoring klinischer Studien mit. Sie überzeugen durch sehr gute Kommunikationsfähigkeit, Verhandlungsgeschick, Verantwortungsbewusstsein, kooperatives Verhalten, Teamfähigkeit und eine zuverlässige Arbeitsweise. Ihre Fähigkeit, wissenschaftliche Sachverhalte klar zu präsentieren und Ihre ausgeprägte Bereitschaft zu Dienstreisen in Deutschland, Österreich und der Schweiz machen Sie zu einem kompetenten Mitarbeiter.

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

Aufgabenbeschreibung:

Als Spezialist im Außendienst (m/w/d) im Raum nördliches Niedersachsen mit Schwerpunkt im Gebiet Stade, Bremen, Nordhorn sind Sie verantwortlich für den Verkauf unserer innovativen kardiologischen Produkte. Sie beherrschen moderne Verkaufstechniken und betreuen und beraten Fachärzte und Apotheker in Kliniken. Sie konzipieren selbstständig Vertriebspläne und innovative Veranstaltungskonzepte für Ihr Gebiet und setzen diese zuverlässig um. Sie beobachten und analysieren den Markt und reagieren umgehend durch die Anpassung Ihres Gebietsvertriebsplanes. Sie sind geübt im Umgang mit modernen Analysemethoden des Außendienstes und entwickeln sich gerne weiter.

Sie arbeiten gerne in crossfunktionalen Teams und Sie sind für die Organisation, Einladung und Durchführung von Fortbildungsveranstaltungen in Ihrem Klinikgebiet verantwortlich. Sie führen Gruppenpräsentationen in der Klinik durch und übernehmen auch Standdienst und Kundenbetreuungen auf nationalen, internationalen Fortbildungsveranstaltungen und Kongressen.

Anforderungen:

Sie haben idealerweise ein natur- oder ein wirtschaftswissenschaftliches Studium abgeschlossen und sind Pharmaberater/in gemäß § 75 AMG oder Sie sind Geprüfte/r Pharmareferent/in und haben Ihre Fähigkeit zum wissenschaftlichen Arbeiten erfolgreich unter Beweis gestellt.  Zudem haben Sie bereits Erfahrung in der Kardiologie oder in anderen Primary Care Bereichen. Sie bilden sich selbstständig kontinuierlich anhand neuester Studien in ihrem Indikationsgebiet weiter, um auf Augenhöhe wissenschaftliche Verkaufsgespräche führen zu können. Sie verbessern Ihre Verkaufstechniken ständig und Ihre analytischen und konzeptionellen Fähigkeiten stellen Sie in Ihrer täglichen Arbeit laufend unter Beweis. Zudem verfügen Sie über  gute Englischkenntnisse, so dass Trainings und wissenschaftliche Publikationen in englischer Sprache für Sie kein Problem darstellen. Mit den Analyse-Tools des Außendienstes gehen Sie sicher um, sehr gute PC-Kenntnisse runden Ihr Profil ab. Sie nutzen Ihr kommunikatives Talent, denken konstruktiv und strategisch, um neue Kundenkontakte aufzubauen und bestehende Geschäftsbeziehungen zu vertiefen. Mit Ihrer erfolgsorientierten, gut organisierten, eigenverantwortlichen und teamorientierten Arbeitsweise überzeugen Sie Ihre Geschäftspartner und tragen damit zur Erreichung der gemeinsamen Ziele innerhalb der Region bei. Sie haben idealerweise bereits Erfahrungen im Projekt – und Accountmanagement. Der Umgang mit modernen Kommunikationstechnologien ist für Sie selbstverständlich. Räumliche Mobilität und Flexibilität sowie das Potenzial und die Bereitschaft zur Übernahme zukünftiger Führungsaufgaben im Marketing und/oder Vertrieb komplettieren idealerweise Ihr Profil.

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

Responsible for all regulatory activities related to assigned products and projects in the role as Regulatory Sciences Manager The Netherlands. Support the Lead GRS The Netherlands.

Reporting to the Lead GRS The Netherlands, manages the daily regulatory activities in Belgium & Luxembourg acquiring and increasing a working knowledge and understanding of BMS products and regulatory processes.

Position Responsibilities

• Manage regulatory processes in line with business/R&D objectives to ensure timely registration of new products/line extensions and variation applications of BMS products.
• Liaise with the Regulatory Agencies in The Netherlands for assigned products.
• Responsible for assuring that approved labelling (SmPC, PL, pack) is implemented in production in accordance with local legislation and BMS procedures
• Monitor and lead the implementation of solutions to changes in legislation and Heath Authority processes.
• Work with local Medical, Marketing, Market Access, Quality and Global Labeling to ensure that regulatory aspects of labeling comply with local legislation and BMS requirements.
• Provide strategic input into product labeling texts (SmPC/PIL) and qualitative review of labelling materials in local language(s), ensuring compliant implementation.
• Responsible for regulatory translations for Benelux and coordination of translations in country (as applicable).
• Oversee the submission of variation applications and approvals for nationally approved products in The Netherlands.
• Responsible for Drug Safety related GRS tasks as per Drug Safety BMS procedures (DHPC, aRMA) and in collaboration with local Drug Safety.
• Responsible for filing clinical trial applications to the competent regulatory authorities in The Netherlands, and all following interactions, in line with BMS company policies and practices, the European Clinical Trial Directive (and subsequent CTR) and local legislation.
• Support the approval process of Early Access Programs (Compassionate use/Medical need programs) and having thorough understanding of required EAP legislation and processes
• Responsible for archiving of regulatory files and documentation, and maintenance of regulatory databases.
• Support local projects, regulatory and department related assignments.
• Act as the key GRS partner for the assigned therapeutic area with the country Business functions, Medical function, Clinical Operations function, Market Access function and Quality function.
• Support launch activities and provide key pre-launch support.
• Responsible for the review and approval of Advertising & Promotional materials in The Netherlands as per the local legislative framework and Ethical Code, and BMS´s procedural documents.
• Support reimbursement processes to ensure timely negotiations and approvals in accordance with business objectives.
• Support development and maintenance of the Benelux Regulatory QMS. Create and update local procedural documents.
• Keep up to date with the regulatory environment within the industry.
• Develop the necessary external contacts with e.g. Health Authorities, Regulatory Agencies and building a key network with Trade Associations.
• Establishes and maintains co-operative working relationships with peers and co-workers.
• Contribute to a high performing organisation and culture by developing and performing in a strong regulatory team.
• Continues to upgrade experience by participating in BMS sponsored training to develop technical skills, communication effectiveness and leadership potential.

Requirements

• Science degree, preferably medical, pharmaceutical or other life science
• Experience in (local) regulatory affairs in a multinational pharmaceutical company
• Experience or very good understanding of the registration process of pharmaceuticals in the EU or BeNeLux
• Knowledge of Good Practices (GMP, GDP, GCP) and quality systems used during stages of manufacture, testing, release, transportations and storage of medicinal products.
• Experience in working with senior regulatory affairs staff on a full range of regulatory tasks.
• Pays strict attention to detail and accuracy whilst maintaining a sense of urgency. Strives to maintain a high level of quality.
• Demonstrated ability in planning, problem solving and time management
• Demonstrated ability in working in a matrix organization and influencing of people in cross-functional teams
• Demonstrated ability in acting as a credible, influential spokesperson in working with senior staff and with peers in related functions.
• Understanding of BMS business processes and working practices
• Fundamental knowledge of BMS product portfolio
• Ability of independent scientific thought, and the capacity to learn and understand new scientific concepts and ideas
• Fluent in Dutch and English.

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

Position: Health Economics & Outcomes Research Manager (HEOR)

Division/Department: Health Economics and Outcomes Research (HEOR)

Function: Market Access, BMS UK & Ireland

As a Health Economist in Bristol-Myers Squibb you will:

• Demonstrate the value of BMS products from an economic perspective and present this evidence with clinical arguments to UK Health Technology Appraisal bodies: NICE, SMC, AWMSG and NCPE.
• Manage the full cross functional process of UK and Ireland HTA submissions from feasibility analysis through to dealing with outcomes post submission.
• Manage business relationships with all relevant customers with regards to HTAs, including physicians, patient groups, academics, economists, HTA bodies.
• Liaise with other members of the BMS cross-functional team on health economic activity e.g. developing RWD to support value story, supporting the BMS UK field access teams with tools such as budget impact models.
• Build strong relationships with medical and economic key opinion leaders, organisations and industry peers to strengthen BMS image, competitive position and performance.

To be considered for the position of HEOR Manager:

Key requirements
• Postgraduate qualification in Health Economics or related discipline  

• Working knowledge of HTA decision making processes.
• Experience of working in a Pharmaceutical company as a Health Economist/HEOR consultancy.

• Experience of working on a UK HTA submissions is highly desired but not mandatory.
• Oncology Therapy Area knowledge desirable.
• Life Sciences Degree / Health Economics Degree

Other requirements
• Demonstrable strong project management experience.

• Excellent communication skills with ability to lead cross functional team in an inclusive manner whilst delivering successful HTA dossiers on time
• Experience of working within a matrix environment.
• Be solutions orientated with a demonstrable how can we attitude

• Established network of HTA and academic thought leaders

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

MAJOR DUTIES AND RESPONSIBILITIES

• Acts as an expert facilitator of Meetings & Events with respect to Health Care professionals, venue contracting and coordination of invitations, travel logistics, material preparation and  budget management from event initiation through execution and close out.
• Accountable for own actions contributing to the execution of all events, in accordance with BMS Standard Operating procedures (SOPs) as well as statutory compliance requirements for the local market.  Conducts due diligence across all activities
• Develops and maintains strong relationships across the matrix environment, building alignment and strong communication with multiple internal and external stakeholders
• Collaborates with other experts including EMCOE, Strategy and Ops,  Legal & Compliance, Global Expenditures, , Global HCP, Congress & Meetings Management, and Business control, seeking advice where appropriate
• Proactively seeks opportunities for process simplification, seeks input and engages the support from multiple stakeholders
• An expert facilitator on contract management, advising stakeholders on the HCP contracting process within the local market and simple cross border activities.
• Supports driving the strategy for continuous improvement with standardization, automation and process simplification.
• Responsible for ensuring speed with escalation and resolution of issues relating to meetings management and HCP payments
• Supports the meetings Management Business Partner with implementation of training in both the local market and cross border, supports the development of training materials and maintenance of local market SharePoint site.

KNOWLEDGE, SKILLS, and COMPETENCIES:

Education/Experience

• Insight and experience of having worked in a sales/marketing environment  or experience in a commercial customer facing role with a minimum of 1-2 years’ experience
• Business or technical undergraduate degree or recognised professional qualification
• Experience of leading and managing small to medium scale projects with complexity
• Experience in Contracting,  HCP Payments, Event Management in the HCP transactions area
• Has a comprehensive understanding of internal compliance processes and external statutory code requirements across the local market, including transfer of value reporting in relation to HCP meetings and transactions and HCP tiering/payment rates
• Understanding of corporate infrastructure and deployment methodologies in order to drive continuous improvement
• Fluency in English and local language

Functional / Technical

• Demonstrated team orientated approach with examples of local leadership
• Demonstrated ability to work independently and effectively in an internal and external matrix environment, with strong interpersonal and influencing skills
• Strong written and verbal communication to facilitate relationships with peers and management
• Demonstrated ability to assess, escalate where appropriate and promptly resolve problems
• Demonstrated ability to apply strong quantitative and analytical skills to provide business solutions with a customer-centric focus
• Demonstrated ability to effectively manage own workload in line with business needs
• Proven ability to demonstrate an innovation mind-set, including simplification of processes
• Demonstrated high level of proficiency in using IT and online systems for managing processes and reporting purposes

DEVELOPMENTAL VALUE

• Opportunity to directly impact customer experience
• Development of effective collaboration skills working across the matrix with a wide range of business partners
• Opportunity to develop Local leadership across own market
• Provide support for training and project implementation across own and other markets
• Develop the ability to effectively communicate, negotiate challenging situations and positively influence change
• Develop an expert understanding of the changing healthcare environment and the customers within it
• Opportunity to take ownership for specific processes and small to medium scale projects with involvement in complex activities
• Opportunity to work within a global or regional team, with technically and culturally diverse people

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

Role Description:

The Associate Director, Patient Operations is accountable to manage onboarding and on-going performance of Apheresis Centers used for BMS Clinical and Commercial Chimeric Antigen Receptor (CAR) T-cell Therapies in Europe. 

This role will be based out of the corporate offices in Boudry, Switzerland and will be responsible for hiring and managing the local and/or regionally based team that will perform the related duties for sites across Europe.  This position reports to the Supply Chain & Apheresis Lead, Europe CAR-T. Travel up to 30% of time within Europe and 5% outside of Europe may be required. 

Come join BMS for this unique opportunity to be part of the team building a leading edge Clinical and Commercial CAR T Platform that serves our patients with novel BMS CAR T Therapies.

Responsibilities will include, but are not limited to the following:

• Lead the Apheresis Network Operations Team responsible for onboarding and management of BMS’s clinical and commercial cell collection site network in Europe.
• Manage the team of Specialist that will work closely with the Commercial CAR-T Affiliates and Clinical Trial teams for collection site onboarding and maintenance programs.
• Ensure team is adequately trained and performing site onboarding and management duties in accordance with BMS global procedures.
• Ensure cell collection site launch plans are developed and maintained to support clinical trials and commercial products.
• Monitor regional onboarding status to ensure compliance with the launch plan and ensure risk mitigation plans are in place for sites where timelines are at risk.  Report any issues to Patient Operations leadership and other stakeholders.
• Collaborate with Quality Assurance and Global Quality Compliance to ensure that the cell collection centers are compliant with all necessary regulations and company policies/procedures as applicable.
• Collaborate with other regional Apheresis and Quality heads (North America and Japan) to ensure global procedures, training materials and electronic systems are adequate to support all areas. Ensure local work instructions are written and maintained as needed.
• Implement customer feedback program to support continuous improvement in region
• Track and monitor defined global apheresis related KPI’s for the region and ensure action plans are developed and implemented for areas where targets are not met.
• Ensure process or system changes are rolled out to regional collection center network within the required timelines.
• Train internal and external stakeholders on the apheresis processes and requirements

Qualifications and Experience Requirements:

• Undergraduate Degree in Life Sciences, minimum 8 years of experience in a regulated environment either hospital or pharmaceutical/biotech
• Experience working in Cell Therapy, Apheresis or Stem Cell Transplant programs
• Experience working in a regulated environment (cGMP/GCP/GCTP) preferred
• Written and verbal fluency in English
• Good understanding of applicable regulations and standards
• Demonstrated excellent leadership, communication and presentation skills
• Independently motivated, detail oriented and good problem-solving ability
• Highly collaborative team player who fosters open communication and facilitates mutual understanding and cooperation between all stakeholders
• Ability to navigate and be successful in a fast-paced, highly-matrixed work environment.
• Willingness to travel, domestically and internationally (~20-30% of time)
• Preferred but not required:
• Advanced degree in the Life Sciences or Engineering (e.g. Pharm D, NP, PA, Biomedical Engineer)
• Experience working in Apheresis, Cellular Therapy or Stem Cell Transplant programs
• Prior customer facing role in pharmaceutical/biotech industry
• Experience working with critical raw material suppliers or contract manufacturing organizations

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

The Mechanisms of Cancer Resistance Thematic Research Center at BMS is one of the fundamental research and early development engines delivering oncology therapeutics to patients.  The scientists at this state-of-the-art research and development site focus on novel tumor intrinsic targets and pathways for tumors that are refractory to current Immuno-Oncology and Oncology therapies, and implement our discovery platforms across all of our therapeutic areas of focus.  We are a fully integrated drug discovery through translational and early clinical development organization which exploits state-of-the-art in vitro, in vivo and ex-vivo models of cancer biology to identify and validate targets.   We partner closely with colleagues in Translational Medicine, Informatics and Predictive Sciences and Early Clinical Development to generate biomarker and patient enrichment hypotheses to enable efficient decision making in early clinical trials.  We are optimally positioned to complement the world-class translational expertise, biology and leading academic research centers in the area.

CORE JOB FUNCTION(S):

• LAB BASED role. Using  current/new techniques to address questions of drug mechanism of action, drug combinations and sensitivity/resistance. Develop and qualify new PD marker assays

• Set up and utilize a wide range of in vitro oncology models

• Design and execute experiments to characterize small molecule inhibitors

• Interact with project teams and contract laboratories for design and oversight of molecular, cellular and/or in vivo studies

• May be responsible for co-authoring non-clinical pharmacology study reports and scientific publications

• Expected to understand departmental goals and development processes

• Execute experiments independently, troubleshoot as needed

• Interpret and discuss data

• Familiar/keeps current with literature

• Communicate via email, meetings and reports

• Responsible for the completion of assignments that have an impact on functional goals

KNOWLEDGE/SKILLS/ABILITIES (KSA's):

• At least 5 years of post-college research experience in the field of molecular/cell biology, physiology, toxicology, translational development or pharmacology or another relevant field.

• Industry experience in drug discovery or translational research in the pharma or biotech setting is a plus

• Ability to conduct experimental work independently, with accurate, detailed record-keeping.

• Ability to efficiently manage and prioritize multiple projects, coordinating in-house research with collaborative work

• Ability to summarize and interpret scientific data in a clear, concise and accurate manner

• Extensive experience performing laboratory work, including handling cell cultures and performing analysis of protein and DNA/RNA samples using a variety of methodologies.

• Experienced in the design and development of cell based assays using various technology platforms.

• Experience in oncogenic signaling pathways is a plus.

• Experience in one or more of the following techniques is expected: Flow cytometry, western blotting, cell culture, cell cycle and apoptosis assays in single or multiplexing formats, qPCR/RT-PCR.

• Excellent oral and written communication skills

• Strong problem-solving skills

• Able to be flexible in case of changing priorities

• Should have solid understanding of relevant scientific principles

• Able to identify scientific and technical problems and potential solutions

• Able to work independently and as a part of a team

• Able to provide input into experimental designs

• Able to interpret data/questions independently and articulate recommendations for resolution with strong scientific rationale

• Able to recognize risks and develop contingency plan.

• Able to communicate with peers and supervisors

• Able to begin to contribute to the achievement of workgroup/team goals

• Key contributor to collaborative efforts

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

We are seeking exceptionally talented and highly motivated synthetic/medicinal chemists who are passionate about joining our fast-paced medicinal chemistry group in the pursuit of discovering innovative therapies. The successful candidate will be an expert in the field of organic synthesis and have hands on experienced with a wide range of modern synthetic transformations.  The candidate will have demonstrated an independent ability in designing and executing on synthetic routes to target molecules, demonstrate a hypothesis driven troubleshooting approach and analytical data interpretation. An understanding of medicinal chemistry concepts and interpretation of biological data is a plus but not required. Good communication skills and a naturally collaborative style are necessary for effective drug discovery team participation.

Qualifications

• Ph.D. with 0-2 years postgraduate experience.
• M.S. degree with 2-4 years or a B. S. degree with 4-8 years of external research experience
• Demonstrated record of productivity in organic or medicinal chemistry research as evidenced by publications and/or patents.
• A strong commitment to experimental work – skilled in multi-step synthesis, purification, and characterization of organic compounds

• In-depth knowledge and hands-on experience with a wide range of state-of-the-art techniques in synthesis, purification, and spectroscopic characterization of novel compounds (NMR, LC-MS, HPLC, etc.).
• Proficient with SciFinder, Chemdraw, and other chemistry-related software
• General knowledge of the drug discovery and development process.
• Familiarity with fundamentals of Medicinal Chemistry and analog design a plus but not required
• Demonstrated ability to work effectively in a fast-paced, highly integrated team environment
• Highly collaborative, self-motivated, team-oriented individual, with good computer skills.
• Excellent written and oral communication skills, demonstrated ability to write peer reviewed quality work or invention disclosures for patent applications, technical reports.

Fit with BMS Culture and Values

• Diversity, inclusion and integrity
• Strong team orientation; highly collaborative
• Solutions and results-oriented focus
• Hands-on approach; resourceful and open to diverse points of view

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

Bristol-Myers Squibb is a global Biopharma company committed to a single mission to discover, develop and deliver innovative medicines focused on helping millions of patients around the world in disease areas such as oncology, cardiovascular, immunoscience and fibrosis.

Join us and make a difference.  We hire the best people and provide them with a work environment that places a premium on diversity, integrity, collaboration and personal development.   Through a culture of inclusion, we create a better, more productive work environment.  We believe that the diverse experiences and perspectives of all our employees help to drive innovation and transformative business results.  

Position:  Supply chain Integration Digitization excellence 
Location:  New Jersey

Position summary
Leads supply chain digital master data execution strategies for integrations and divestitures including digital and data technologies.  

Roles and responsibilities
•    Lead or coordinate digital supply chain / master-data integration projects resulting from mergers or divestitures.
•    Identify and evaluate opportunities to maximize supply chain effectiveness through digital and data technologies throughout the integration or divestiture process
•    Develop and implement appropriate data management strategies and transition plans to ensure on-going business operations are not disrupted through the transition 
•    Assesses the impact of digital supply chain integration plans on day-to-day operations. 
•    Lead implementation of operational change initiatives across geographies where required to ensure smooth transition to harmonized supply chain data or digital technology systems
•    Drives project management of digital and data integration programs 
•    Devise execution strategies to meet program timelines and deliverables
•    Identify, design and generate standards to promote efficiencies for end-users of supply chain data and digital technologies.  Identify and share best-practices

Requirements
•    Bachelor’s degree required in engineering, business, data science or information systems with a Masters or MBA preferred.
•    Over 10 years of experience in operations, supply chain, manufacturing, ERP, digital / data technologies, quality, cell therapy in the biopharma industry
•    Operational excellence experience (Green/Black belt or equivalent) preferred 
•    Proven ability to develop and lead global teams
•    Ability to navigate organization, and identify, align and integrate cross-functional resources into cohesive teams in a highly matrixed environment
•    Demonstrated supply chain acumen and experience implementing enterprise technology or data systems including change management
•    Proven ability to identify innovative ideas through deployment that optimize processes / create value
•    Excellent interpersonal, written and verbal communication skills
•    Excellent analytical and problem solving skills
•    Ability to work in a fast-paced environment, organized and able to prioritize program execution activities to meet multiple deadlines
•    Business acumen to develop meaningful business cases
 

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

PURPOSE AND SCOPE OF POSITION:

The main purpose of the Facility and Reliability Engineer is to implement a continuous improvement strategy to support the New Jersey GMP Facilities to maintain a qualified and regulatory compliant Facility Operation status.  Main responsibility will be the execution of the reliability program and oversite of quality systems for facility related items for all GMP and Non-GMP utility equipment and instrumentation.  The Lead Facility & Reliability Engineer will lead small-scale capital and expense projects (20K to 250K) and coordinate large-scale capital projects with Global Engineering to support the GMP facility operations within New Jersey.  The incumbent in this role will have specific job tasks and processes to follow to perform their job.  The Lead Facility & Reliability Engineer supports the successful operation of facility, laboratory and business functions at multi-use GMP sites within New Jersey through interaction with internal customers and external service providers.   The role is expected to be able to identify issues or unmet needs and initiates projects or programs to address them.  This individual works collaboratively to complete assignments and oversees the successful completion of tasks.  Using solid analytical skills, the incumbent can recognize problems of moderate scope and complexity, and independently, develop potential solutions and courses of action.  This individual represents the work group on multi-disciplinary and cross-functional teams and uses established relationships to influence and lead teams and stakeholders with fact-based, business value knowledge.

DUTIES AND RESPONSIBILITIES:

Facility Asset Management

• Provides technical expertise, troubleshooting and improved equipment maintenance/reliability strategies to optimize safe, compliant, and efficient operations of all facility and utility equipment and instrumentation.
• Prepares asset files including equipment data sheets, impact assessments, P&ID & drawings, factory O&Ms, factory maintenance recommendations, maintenance work plans and procedures.
• Assist in the development and management of a facility document management program to track facility drawings, and project turnover packages.
• Lead on facility workstream to support large-scale project asset and maintenance plan management.  Project will require the ability to identify and manage contract support to execute according to project schedule.
• Manage logbook strategies for facility equipment owned and maintained by GMP Facilities.

Preventative Maintenance Work Plans

• Establishes effective preventative and predictive maintenance plans for GMP Pharmaceutical facility & process utility equipment according to OEM recommendations, industry standards and process application
• Generates SOPs and Work Practices within Celgene’s Document Management System and electronic work plan template and measurement data templates to establish the Use, Maintenance and Calibration plans for GMP equipment.
• Works with vendors to define vendor requirements to support maintenance or calibration plans and contracts.
• Initiates deviations for maintenance work orders that are out of compliance
• Manages any CAPAs associated with the CMMS, including PMs or Calibrations performed late or out of conformance

Reliability Program

• Execute criticality assessments for equipment and components
• Execute FMEA, RCA and identify alterative options to reduce or eliminate risk
• Execute Historical trends to evaluate the criticality assessment, FEMA and RCA for periodic review.    

Continuous Improvement

• Reviews completed demand work orders for compliance with change control and like-for-like procedures
• Conducts Historical Performance Reviews on GMP Direct Impact assets and Critical instrumentation maintained and calibrated by the GMP Facilities Department
• Initiates deviations for demand maintenance work orders or preventative maintenance activities that are out of compliance
• Support and track deviations, investigations and CAPA plans for the GMP Facilities Department.  Role will include conducting detailed investigations to determine root cause and necessary CAPAs by working cross functionally with Facility Management, QA, Validation and Business Area Management.
• Implement predictive maintenance tools to identify equipment trending to failure to implement repairs prior to failure.

• Support facility operations by providing operational SOPs to manage GMP facility and equipment operations.  Procedures may include a USP Water System Operational Procedure or Facility Cleaning.

• Promotes and maintains compliance with corporate, safety, security and regulatory policies.
• Maintains all assigned Corporate, Facilities, GMP and EHS training as required
• Oversee the LOTO and Confined Space procedures for GMP Facility owned and maintained equipment.

REQUIRED COMPETENCIES:  Knowledge, Skills, and Abilities:

• Strong understanding of building systems including life-safety, lighting, mechanical, electrical, and plumbing
• Strong knowledge of critical utility systems such as compressed gas, vacuum, waste, as well as security and key managements systems and policies
• Strong knowledge of facility management systems such as CMMS (Computerized Maintenance Management Systems). 
• Maintains a high level of multi-tasking ability in conjunction with proven organizational skills.  Ability to organize assigned tasks in a high paced GMP environment and concurrently monitor tasks / assignments with others that may impact timely completion.  Ability to effectively manage multiple tasks and activities simultaneously.
• Familiarity with FDA / cGXP environments and associated compliance regulations
• Adept in Microsoft Office Suite – Word, PowerPoint, MS Project, Excel and Outlook, Visio and the ability to learn new software, such as enterprise business, building management, security, and maintenance management systems.
• Proficient at writing well-formulated emails and notifications.  Ability to effectively communicate with employees, contractors and vendors.  Ability to follow oral and written instructions, read, interpret and update engineering manuals/drawings relevant to the trade or the assigned task
• Self-starter who is able to work both independently without direct supervision or in a team environment
• Knowledge of FDA regulations, IBC/IFC building codes, OSHA, NFP, FM, LPDS and UL

Competencies:

• Technical Knowledge
• SOP writing skills
• FMEA
• Problem Solving / Troubleshooting
• Team Player
• Multi-tasking
• Customer Focus
• Action Oriented / Tenacity

Education and Experience:

• BS degree in mechanical, electrical engineering or similar engineering field
• Minimum 5-8 years of facilities maintenance/operations experience at an industrial or commercial site or related experience and/or equivalent combination of education and experience
• 2-5 years of GMP facility experience preferred but not required

WORKING CONDITIONS (US Only):

Physical / Mental Demands:

• Occasional stooping, bending, stretching, pushing, pulling, reaching and/or lifting up to 50lbs
• Ability to sit, stand, walk and move within workspace for extended periods
• Ability to perform repetitive tasks including frequent hand to finger manipulations, grasping, pushing and pulling
• Ability to climb ladders and work in elevated areas.

Environmental Conditions:

• Primarily office environment
• Ability to work safely in an environment with hazardous, radioactive, and infectious materials and waste.
• Ability to work safely in an environment with exposure to high temperature / pressure steam, and other fluids, compressed gasses, odors, various noise levels, moving parts, vibration, wet/slippery areas and high voltage energy supplies
• Environment may include working at heights, in cold temperatures, and/or constricted spaces
• Ability to work safely when working alone, or working with others.

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.