Job Details

Associate Director, Preclinical Biostatistics

Clinical Dev

icon-location-marker Princeton - NJ - US
icon-location-marker Berkeley Heights - NJ
Posted 37 days ago Full_time R1547286

At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

The Associate Director, Preclinical Biostatistics (ADPB) collaborates with preclinical scientists from cross-functional discovery and preclinical biomarker research teams, representing the BMS Global Biometrics and Data Sciences (GBDS) statistical community.

Job Responsibilities:

  • Independently collaborates with scientists from cross-functional discovery and preclinical biomarker research teams including, but not limited to, biologists, chemists, imaging specialists, pharmacokinetic/pharmacodynamic scientists, and early clinical development physicians and scientists.  Independently collaborates with the Early Clinical Biostatistics Lead and the Translational Medicine Statistics Lead in GBDS as a therapeutic candidate progresses from discovery to early clinical development.
  • Independently leads efforts on innovative, state-of-the-art, Bayesian and frequentist in vivo animal study designs and in vitro assay designs.
  • Independently plans and conducts the corresponding rigorous statistical analyses.
  • Visually summarizes results of statistical analyses providing relevant insight, interpretations, and contributions to decision making.
  • Individually or jointly with discovery scientists, communicates the experimental results, their interpretations, and research decisions, through internal and external presentations, documents, and publications.
  • Enables and contributes to quantitative strategic decision making and risk assessment in advancing therapeutic candidates through discovery to early clinical development.
  • Independently or in collaboration, may conduct statistical research targeted at solving discovery and preclinical biomarker research problems.    
  • Implements or develops statistical software programs and tools for experimental design, data analysis, simulation, and conducting research.
  • Quantitatively empowers the discovery scientists by increasing their stochastic intelligence and statistical literacy through 1-on-1 or small group mentoring, or larger applied statistical seminars.
  • Keeps up to date with state-of-the-art statistical methodology.
  • Develops expertise beyond biostatistics by reading the discovery, preclinical biomarker, and medical literature.
  • Accountable for ensuring the integrity, quality, and timeliness of all ADPB job responsibilities and functions.
  • Builds the external reputation of BMS R&D via external interactions through collaborations with alliance partners, academic and government research organizations, key opinion leaders, as reflected through professional conference participation, and publishing in the discovery, preclinical biomarker, and statistical literature.

Education / Experience:

  • Ph.D. (or equivalent) in Biostatistics, Statistics, or related field with 7+ years pharmaceutical research, development, or related experience.  
  • Demonstrated knowledge and application of Bayesian and frequentist design-to-decision making strategies in pharmaceutical research, development, or related field.
  • Excellent statistical computing skills, including simulation.
  • Demonstrated efficiency with software, for example, but not limited to, some combination of:  R, RStudio, SAS, JMP, OpenBUGS, JAGS, Stan, FACTS, Spotfire, East, NQuery Advisor, and GraphPad Prism. Working knowledge of MS WORD, MS EXCEL, MS PowerPoint, and Adobe Acrobat.
  • Excellent oral and written communication skills.
  • A keen interest in scientific inquiry, a positive “can do” philosophy, accompanied by a high level of emotional intelligence and maturity for building effective collaborative partnerships producing impactful discovery and preclinical biomarker research.
  • Additional favored experience:
    • 1-1 or small group mentoring, larger group seminars or courses.
    • Published statistical research.
    • Published collaborative preclinical or clinical research.
    • Internal or external statistical presentations.
    • Internal or external collaborative preclinical or clinical presentations.

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. 

Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.

To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation.  Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment.  This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.

Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application or if you are applying to a role based in the U.S. or Puerto Rico and you believe that you are unable to receive a COVID-19 vaccine due to a medical condition or sincerely held religious belief, during or any part of the recruitment process, please direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

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