Senior Research Scientist, NGS

Drug Discovery Research

icon-location-marker Cambridge - MA - US
Posted 21 days ago Full_time R1518245

Bristol-Myers Squibb is a global Biopharma company committed to a single mission: to discover, develop, and deliver innovative medicines focused on helping millions of patients around the world in disease areas such as oncology, cardiovascular, immunoscience and fibrosis.

 

Join us and make a difference.  We hire the best people and provide them with a work environment that places a premium on diversity, integrity, collaboration and personal development. Through a culture of inclusion, we create a better, more productive work environment. We believe that the diverse experiences and perspectives of all our employees help to drive innovation and transformative business results.

We seek a highly motivated, detail-oriented Senior Investigator with broad experience in application of genomics method in understanding Disease Biology with particular emphasis in cancer genomics. The scientist will be a strong contributor to the core Genomics Group that works with investigators across the company. The position will be part of an integrated team dedicated to understanding the mechanisms of Cancer resistance to therapy among other things. Primary responsibilities include various genomic and transcriptomic assay development and implementation in support of programs across multiple therapeutic areas, new genomic assay development and optimization, establishing collaboration across genomics ecosystem in Cambridge.

Responsibilities

Design and implementation of genomic assays in support of various research programs.

Play key role in optimizing existing NGS methods or developing new NGS protocols to suit needs.

Co-ordinate with investigators to execute genomics project data and analysis in a timely manner.

Manage NGS instrument operation and Maintenance.

Manage Research scientists to deliver genomic data to investigators

Coordinate NGS data analysis perform data interpretation

Manage outreach and collaborations with Cambridge genomics community

Maintain lab notebooks, compiles data, and details written experimental instructions, particularly in areas involving new technology and/or novel experimental approaches.

Requirements

The successful candidate will have Ph.D. in Molecular/Cell Biology or Genetics or Biochemistry with at least 2 years or M.S in Molecular/Cell Biology or Genetics with at least 5 years of relevant scientific lab experience with emphasis on applied genomics.

Broad hands-on experience in molecular Biology methods relevant to genomics

Experience applying genomic methods in Disease biology questions

Experience in NGS library generation and associated methods.

Experience in advanced Cell and Molecular Biology technique is essential.

Familiarity with NGS data analysis and data interpretation

Experience in working with FFPE and other clinical sample handling preferred.

Expertise in Cell separation technologies such as FACS/Microfluidics is a plus but not essential.

Ability to communicate effectively and manage projects

Extensive people and project/matrix team experience, with demonstrated ability to work effectively within multidisciplinary teams

Bristol-Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees the resources to pursue their goals, both at work and in their personal lives.