Research Scientist/Research Investigator, Protein Purification (15)

Drug Discovery Research

icon-location-marker Redwood City - CA - US
Posted 42 days ago Full_time R1515551

We are seeking a skilled protein chemist at the Research Scientist or Research Investigator level (based on experience) to join the expression and purification group. The candidate will be expected to work on a variety of projects to purify antibodies from multiple species and heterologous expression systems.   

Specific Responsibilities

Purify proteins using variety of systems (affinity, ion exchange, size exclusion, etc.).

Purify proteins using multiple purification platforms (i.e. AKTA Avant, etc.).

Analyze proteins using standard protein characterization methods (SDS-PAGE/CE-SDS, SEC-MALLS, endotoxin, etc.).

Perform experiments with strong attention to detail and documentation.

Excellent written and oral skills are necessary.

Accomplish goals under project team time lines.


Requirements

Ph.D. with postdoctoral experience or MS degree with 5+ years of industry experience required. The degree should be in Biochemistry, Biophysics, Molecular and Cell Biology, or a similar field.

Experience in generation and characterization of high quality proteins for immunizations, crystallography, or other uses is required. The ideal candidate should have demonstrated independence in experimental design, execution, data analysis, and troubleshooting.

Strong expertise in antibody purification and characterization for in vitro and in vivo uses is highly preferred.

Experience in automated purification is highly preferred.

Experience and knowledge of molecular biology and expression is preferred.

Experience with characterization of antibodies for development attributes and familiarity with downstream development is a plus.

Excellent interpersonal skills are required with the ability to interact effectively with people, both internally in a multidisciplinary biologics discovery team and externally across the organization.