Areas of Interest & Competitive Research Grants - Bristol Myers Squibb
Areas of Interest (AOI)
Bristol Myers Squibb seeks Independent Research applications across all therapeutic areas. Our Areas of Interest outline additional criteria to help guide the scientific community. All concept applications submitted that best align with our interests will be considered and evaluated. Concepts may be submitted outside of the posted AOIs, but the threshold for approval may be relatively high.
The criteria will include, but not be limited to:
- Specific therapeutic area of interest
- The type of science we are seeking
- We may include a specific window of time for all concept applications to be submitted
| Therapeutic Area and / or Asset | AOIs Posted on BMS.com | Pre-Concept Submission Period | |
| Start Date | End date | ||
| Hematology | 23-Nov-20 | 18-Jan-21 | 5-Feb-21 |
| Immunology – ZEPOSIA® (ozanimod) Multiple Sclerosis | 23-Nov-20 | 4-Jan-21 | 22-Jan-21 |
| Immunology – ZEPOSIA® (ozanimod) Ulcerative colitis | 2-Dec-20 | 4-Jan-21 | 29-Jan-21 |
| Immunology - ORENCIA® (abatacept) | 9-Dec-20 | 18-Jan-21 | 5-Feb-21 |
| Oncology | Jan 2021 | 29-Mar-21 | 23-Apr-21 |
Multiple Sclerosis – Zeposia (ozanimod) ISR Areas of Interest – 2021 RFP Cycle 1
In scope:
- Ozanimod efficacy and safety in early RMS disease and/or diverse patient populations
- RMS disease outcomes to include novel endpoints such as cognition, neuroimaging, biomarkers and/or patient reported outcomes
- Exploring the impact of ozanimod on immune function (in vitro/in vivo)
- Direct effect of ozanimod in the central nervous system using advanced imaging or human cell-based models
Out of scope:
- Pediatric studies
- Indications outside of multiple sclerosis
- Combination with other disease modifying therapies
- Alternative dosing other than 0.92 mg QD
Hematology Assets
Myeloid - CC-486 (azacitidine tablets) ISR Areas of Interest – 2021 RFP Cycle 1
In scope:
- Efficacy and safety of CC-486 in HR MDS
- Evaluation of CC-486 combinations in various AML subpopulations
Myeloid - Luspatercept ISR Areas of Interest - 2021 RFP Cycle 1
In scope:
- Evaluation of epidemiology, disease burden, and treatment patterns by country and region for B-thal
- Luspatercept alone and in combination with other therapies in MDS and B-thal
- Effect of luspatercept on comorbidities and other physiological functions related to iron overload
- Hematologic improvements of luspatercept on cell lineages beyond erythroid
- Patient reported outcomes and at-home monitoring
- Luspatercept use in other anemias other than MDS and B-thal
- Luspatercept in conjunction with other treatments/therapies
Out of scope:
- ESA treatment rescue post luspatercept failure
- Luspatercept 1L monotherapy in del5q MDS pts
Myeloid - Fedratinib ISR Areas of Interest - 2021 RFP Cycle 1
In scope:
- Use of fedratinib in other disease areas outside MF
- Efficacy and safety of fedratinib alone and in combination for MF, including subpopulations of patients with high unmet need
Out of scope:
- Fedratinib use as monotherapy in AML and essential thrombocythemia
Multiple Myeloma - Iberdomide ISR Areas of Interest - 2021 RFP Cycle 1
In scope:
- Efficacy and safety of Iberdomide-based therapies in RRMM at first or second relapse
- Efficacy and safety of Iberdomide-based therapies in combination with and following BCMA-targeted therapies
- Efficacy and safety of Iberdomide-based therapies in NDMM, in both the transplant-eligible and –ineligible settings
- Impact of Iberdomide on patient reported outcomes and QOL assessments
Out of scope:
- Combination with melphalan
Multiple Myeloma - Elotuzumab ISR Areas of Interest - 2021 RFP Cycle 1
In scope:
- Role of elotuzumab in combination with CELMoD compounds in patients with RRMM
- Evaluate elotuzumab in combination with CELMoD compounds following BCMA-targeted therapies
Lymphoma - Nivolumab ISR Areas of Interest - 2021 RFP Cycle 1
In scope:
- Novel combinations with nivolumab to augment efficacy in cHL patients with best response of SD or PR
- Novel combinations with nivolumab in r/r cHL to address unmet needs
- If you are a potential investigator who is interested in seeking support to conduct independent research involving Nivolumab in Japan, Taiwan, or Korea, click here
- If you are a potential investigator who is interested in seeking support for independent research using Apixaban, click here.
- If you are a potential investigator who is interested in seeking support for non-clinical research using a BMS product, click here
- If you are a potential investigator who is interested in seeking support for independent research using one of our early pipeline assets, click here
- If you are a potential investigator who is interested in seeking support for independent research involving NKTR-214 (Bempegaldesleukin) & Nivolumab, click here
- If you are a potential investigator who is interested in seeking support for independent research involving idecabtagene vicleucel or lisocabtagene maraleucel, click here
Competitive Research Grants
The Bristol Myers Squibb Competitive Research Grant process includes the submission of a concept application that meets the required criteria posted. Competitive Research Grants we post will include specific criteria that must be met for your application to be considered.
At this time, there are no competitive research grants available.
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