Leveraging biomarkers and diagnostics in personalized medicine is becoming increasingly important in the fight against cancer. Bristol Myers Squibb is pioneering research to better understand cancer biology and its intersection with the immune system.
We are investigating a number of different biomarkers that may help match the right patients with the right treatments at the right time. Select the biomarker name for more information.
Tumor antigens
Biomarkers indicative of tumor mutations and neoantigens:
TMB | MSI-H/dMMR | Neoantigens
Inflamed tumor
Biomarkers indicative of an inflamed tumor:
PD-L1 | PD-L2 | Inflammation Gene Signatures
Immune suppression
Biomarkers indicative of tumor immune-system evasion:
LAG-3 | IDO | Tregs | MDSCs
Host environment
Biomarkers indicative of host environment:
Microbiome | Germline Mutations