Featured Researcher: Amy Sehnert - Bristol Myers Squibb

Amy Sehnert, vice president and global program lead for Cardiovascular Transition Assets in Drug Development at Bristol Myers Squibb’s Brisbane, California site, working to develop precision therapeutics for serious cardiovascular disorders, with a specific focus on diseases of heart muscle (cardiomyopathies) and heart failure. 

Through a precision approach assessing well-characterized patient groups and targeting molecular-genetic underpinnings of disease, Amy and her team diligently work to identify, optimize and develop therapies that may have the most profound impact. Amy and her team use data science, advanced clinical trial solutions and digital innovation to drive Bristol Myers Squibb’s pipeline into action. Amy has led her team through global regulatory filings , which have led to approvals of Camzyos^TM on 5 continents including the US FDA and European Medicines Agency (EMA). She now leads cross-functional teams developing future cardiovascular pipeline assets. 

Amy joined Bristol Myers Squibb in 2020 by way of MyoKardia, where she built and led the clinical team studying the company’s pipeline of therapies for patients with hypertrophic cardiomyopathy, including in Phase 2 and 3 clinical trials. Amy possesses unique expertise in clinical and drug development, including interpretation and presentation of results. She enjoys the collaborative nature of the work from bench-to-bedside. She is a member of the Brisbane Site Executive Leadership Team. She now leads cross-functional teams developing future cardiovascular pipeline assets.

Prior to MyoKardia, Amy led efforts to launch clinical trial programs for genomic diagnostics at GRAIL, Illumina and Verinata Health. Amy started her professional career as an assistant professor at UCSF where she studied the genetics of hypertrophic cardiomyopathy in children and their families, and later transitioned to Stanford University. Amy has also contributed to over 50 scientific publications.

Amy earned her undergraduate, mechanical engineering and doctor of medicine degrees from the University of Minnesota. She completed her residency in pediatrics at the University of Colorado Children’s Hospital, Denver, CO, followed by a fellowship in pediatric cardiology at UCSF.